The flight distance from Vilo Acuna International Airport (CYO) in Cayo Largo del Sur, Cuba to Istanbul Airport (IST) in Istanbul, Turkey is 10,003 kilometers (6,216 miles / 5,401 nautical miles). The estimated flight time for this route is approximately 13h, flying northeast at a heading of 45°.

This is an ultra-long-haul route, one of the longest in aviation. It requires wide-body aircraft with extended range capability such as the Airbus A350-900ULR or Boeing 777-200LR. Passengers should prepare for an extended flight with multiple meal services.

This is an international route connecting Cuba with Turkey. It is an intercontinental flight between North America and Asia. Travelers should check visa requirements, customs regulations, and any travel advisories before booking.

Time zone information: When it's 15:10 in Cayo Largo del Sur, it's 23:10 in Istanbul. With a 8-hour time difference, travelers should plan for significant jet lag. It typically takes one day per hour of time difference to fully adjust.

The return flight from Istanbul (IST) to Cayo Largo del Sur (CYO) follows a heading of 299° (west northwest). Actual flight times may vary depending on wind conditions, air traffic, and the specific aircraft used.

For more information about these airports, visit the Vilo Acuna International Airport (CYO) and Istanbul Airport (IST) detail pages, or use our flight duration calculator to compare other routes.