The flight distance from Vilo Acuna International Airport (CYO) in Cayo Largo del Sur, Cuba to San Diego International Airport (SAN) in San Diego, United States is 3,715 kilometers (2,308 miles / 2,006 nautical miles). The estimated flight time for this route is approximately 5h, flying west northwest at a heading of 297°.

This is a medium-haul route that may be operated by either narrow-body or wide-body aircraft depending on demand. Passengers can expect a meal service on most carriers.

This is an international route connecting Cuba with United States. Travelers should check visa requirements, customs regulations, and any travel advisories before booking.

Time zone information: When it's 06:21 in Cayo Largo del Sur, it's 03:21 in San Diego. The 3-hour time difference may cause some jet lag. Most travelers adjust within a day or two.

The return flight from San Diego (SAN) to Cayo Largo del Sur (CYO) follows a heading of 100° (east). Actual flight times may vary depending on wind conditions, air traffic, and the specific aircraft used.

For more information about these airports, visit the Vilo Acuna International Airport (CYO) and San Diego International Airport (SAN) detail pages, or use our flight duration calculator to compare other routes.