The flight distance from Lisbon Portela Airport (LIS) in Lisbon, Portugal to Cerro Largo International Airport (MLZ) in Melo, Uruguay is 9,177 kilometers (5,702 miles / 4,955 nautical miles). The estimated flight time for this route is approximately 12h, flying southwest at a heading of 217°.

This is an ultra-long-haul route, one of the longest in aviation. It requires wide-body aircraft with extended range capability such as the Airbus A350-900ULR or Boeing 777-200LR. Passengers should prepare for an extended flight with multiple meal services.

This is an international route connecting Portugal with Uruguay. It is an intercontinental flight between Europe and South America. Travelers should check visa requirements, customs regulations, and any travel advisories before booking.

Time zone information: When it's 22:42 in Lisbon, it's 19:42 in Melo. The 3-hour time difference may cause some jet lag. Most travelers adjust within a day or two.

The return flight from Melo (MLZ) to Lisbon (LIS) follows a heading of 34° (northeast). Actual flight times may vary depending on wind conditions, air traffic, and the specific aircraft used.

For more information about these airports, visit the Lisbon Portela Airport (LIS) and Cerro Largo International Airport (MLZ) detail pages, or use our flight duration calculator to compare other routes.