The flight distance from Chicago O'Hare International Airport (ORD) in Chicago, United States to Sao Tome International Airport (TMS) in Sao Tome, São Tomé and Príncipe is 10,361 kilometers (6,438 miles / 5,594 nautical miles). The estimated flight time for this route is approximately 13h, flying east at a heading of 87°.

This is an ultra-long-haul route, one of the longest in aviation. It requires wide-body aircraft with extended range capability such as the Airbus A350-900ULR or Boeing 777-200LR. Passengers should prepare for an extended flight with multiple meal services.

This is an international route connecting United States with São Tomé and Príncipe. It is an intercontinental flight between North America and Africa. Travelers should check visa requirements, customs regulations, and any travel advisories before booking.

Time zone information: When it's 01:27 in Chicago, it's 07:27 in Sao Tome. With a 6-hour time difference, travelers should plan for significant jet lag. It typically takes one day per hour of time difference to fully adjust.

The return flight from Sao Tome (TMS) to Chicago (ORD) follows a heading of 312° (northwest). Actual flight times may vary depending on wind conditions, air traffic, and the specific aircraft used.

For more information about these airports, visit the Chicago O'Hare International Airport (ORD) and Sao Tome International Airport (TMS) detail pages, or use our flight duration calculator to compare other routes.