The flight distance from Tocumen International Airport (PTY) in Tocumen, Panama to Siena / Ampugnano Airport (SAY) in Siena, Italy is 9,369 kilometers (5,822 miles / 5,059 nautical miles). The estimated flight time for this route is approximately 12h, flying northeast at a heading of 47°.

This is an ultra-long-haul route, one of the longest in aviation. It requires wide-body aircraft with extended range capability such as the Airbus A350-900ULR or Boeing 777-200LR. Passengers should prepare for an extended flight with multiple meal services.

This is an international route connecting Panama with Italy. It is an intercontinental flight between North America and Europe. Travelers should check visa requirements, customs regulations, and any travel advisories before booking.

Time zone information: When it's 19:08 in Tocumen, it's 01:08 in Siena. With a 6-hour time difference, travelers should plan for significant jet lag. It typically takes one day per hour of time difference to fully adjust.

The return flight from Siena (SAY) to Tocumen (PTY) follows a heading of 277° (west). Actual flight times may vary depending on wind conditions, air traffic, and the specific aircraft used.

For more information about these airports, visit the Tocumen International Airport (PTY) and Siena / Ampugnano Airport (SAY) detail pages, or use our flight duration calculator to compare other routes.